Publications

Kahraman, T., Akpinar, G. G., Yildirim, M., Larssen, P., Bayyurt-Kocabas, B., Yagci, F. C., Gursel, A., Horuluoglu, B. H., Yazar, V., Ayanoglu, I. C., Yildirim, T. C., Evcili, I., Yilmaz, I. C., Eldh, M., Gabrielsson, S., Guler, U., Salih, B., Gursel, M., & Gursel, I. (2024). Enhancing preventive and therapeutic cancer vaccine efficacy through biotherapeutic ligand-associated extracellular vesicles. Journal of Controlled Release, 376, 618–631. Advance online publication.

Chan, Y. H., Lundberg, V., Le Pen, J., Yuan, J., Lee, D., Pinci, F., Volpi, S., Nakajima, K., Bondet, V., Åkesson, S., Khobrekar, N. V., Bodansky, A., Du, L., Melander, T., Mariaggi, A. A., Seeleuthner, Y., Saleh, T. S., Chakravarty, D., Marits, P., Dobbs, K., Ozcelik, T. … Zhang, S. Y. (2024). SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency. The Journal of Experimental Medicine, 221(9), e20231725.

Atıcı, S., & Çizmecioğlu, O. (2024). Molecular mechanisms of PI3K isoform dependence in embryonic growth. Journal of the Turkish German Gynecological Association, 25(3), 159–166.

Canavar Yildirim, T., Ozsurekci, Y., Yildirim, M., Evcili, I., Yazar, V., Aykac, K., Guler, U., Salih, B., Gursel, M., & Gursel, I. (2024). Immunogenicity and protective capacity of a CpG ODN adjuvanted alum adsorbed bivalent meningococcal outer membrane vesicle vaccine. International Immunology, 36(8), 393–404.

Dalkara, T., Kaya, Z., & Erdener, Ş. E. (2024). Unraveling the interplay of neuroinflammatory signaling between parenchymal and meningeal cells in migraine headache. The Journal of Headache and Pain, 25(1), 124.

Dalkara, T., Østergaard, L., Heusch, G., & Attwell, D. (2024). Pericytes in the brain and heart: functional roles and response to ischemia and reperfusion. Cardiovascular Research, cvae147. Advance online publication.

Gazerani, P., Papetti, L., Dalkara, T., Cook, C. L., Webster, C., & Bai, J. (2024). The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis. Nutrients, 16(14), 2222.

Golla, U., & Chachoua, I. (2024). Editorial: Non-coding RNAs as emerging players in the development, diagnosis, and treatment of cancer. Frontiers in Molecular Biosciences, 11, 1453268.

Kisla, M. M., Yaman, M., Zengin-Karadayi, F., Korkmaz, B., Bayazeid, O., Kumar, A., Peravali, R., Gunes, D., Tiryaki, R. S., Gelinci, E., Cakan-Akdogan, G., Ates-Alagoz, Z., & Konu, O. (2024). Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish. ACS Omega, 9(28), 30594–30614.

Marchal, A., Cirulli, E. T., Neveux, I., Bellos, E., Thwaites, R. S., Schiabor Barrett, K. M., Zhang, Y., Nemes-Bokun, I., Kalinova, M., Catchpole, A., Tangye, S. G., Spaan, A. N., Lack, J. B., Ghosn, J., Burdet, C., Gorochov, G., Tubach, F., Hausfater, P., COVID Human Genetic Effort (Ozcelik, T.), COVIDeF Study Group, … Bolze, A. (2024). Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection. HGG Advances, 5(3), 100300.

Pervin, B., Gizer, M., Şeker, M. E., Erol, Ö. D., Gür, S. N., Polat, E. G., Değirmenci, B., Korkusuz, P., & Aerts-Kaya, F. (2024). Bone marrow mesenchymal stromal cells support regeneration of intestinal damage in a colitis mouse model, independent of their CXCR4 expression. Clinical and Translational Science, 17(5), e13821.

Auerbach, S., Puka, B., Golla, U., & Chachoua, I. (2024). Recent Advances towards the Understanding of Secondary Acute Myeloid Leukemia Progression. Life, 14(3), 309.

Bastard, P., Gervais, A., Taniguchi, M., Saare, L., Särekannu, K., Le Voyer, T., Philippot, Q., Rosain, J., Bizien, L., Asano, T., Garcia-Prat, M., Parra-Martínez, A., Migaud, M., Tsumura, M., Conti, F., Belot, A., Rivière, J. G., Morio, T., Tanaka, J., Javouhey, E., Ozcelik, T., … Casanova, J. L. (2024). Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children. The Journal of Experimental Medicine, 221(2), e20231353.

Lucena, M. I., Villanueva-Paz, M., Alvarez-Alvarez, I., Aithal, G. P., Björnsson, E. S., Cakan-Akdogan, G., Cubero, F. J., Esteves, F., Falcon-Perez, J. M., Fromenty, B., Garcia-Ruiz, C., Grove, J. I., Konu, O., Kranendonk, M., Kullak-Ublick, G. A., Miranda, J. P., Remesal-Doblado, A., Sancho-Bru, P., Nelson, L., Andrade, R. J., … Fernandez-Checa, J. C. (2024). Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet. Pharmacological Research, 200, 107046.

Vural-Ozdeniz, M., Calisir, K., Acar, R., Yavuz, A., Ozgur, M. M., Dalgıc, E., & Konu, O. (2024). CAP-RNAseq: an integrated pipeline for functional annotation and prioritization of co-expression clusters. Briefings in Bioinformatics, 25(2), bbad536.

Bishop, T. R., Onal, P., Xu, Z., Zheng, M., Gunasinghe, H., Nien, C. Y., Small, S., & Datta, R. R. (2023). Multi-level regulation of even-skipped stripes by the ubiquitous factor Zelda. Development (Cambridge, England), 150(23), dev201860.

Karoglu-Eravsar, E. T., Tuz-Sasik, M. U., Karaduman, A., Keskus, A. G., Arslan-Ergul, A., Konu, O., Kafaligonul, H., & Adams, M. M. (2023). Long-Term Acetylcholinesterase Depletion Alters the Levels of Key Synaptic Proteins while Maintaining Neuronal Markers in the Aging Zebrafish (Danio rerio) Brain. Gerontology, 69(12), 1424–1436.

Kaysudu, I., Gungul, T. B., Atici, S., Yilmaz, S., Bayram, E., Guven, G., Cizmecioglu, N. T., Sahin, O., Yesiloz, G., Haznedaroglu, B. Z., & Cizmecioglu, O. (2023). Cholesterol biogenesis is a PTEN-dependent actionable node for the treatment of endocrine therapy-refractory cancers. Cancer Science, 114(11), 4365–4375.

Le Voyer, T., Parent, A. V., Liu, X., Cederholm, A., Gervais, A., Rosain, J., Nguyen, T., Perez Lorenzo, M., Rackaityte, E., Rinchai, D., Zhang, P., Bizien, L., Hancioglu, G., Ghillani-Dalbin, P., Charuel, J. L., Philippot, Q., Gueye, M. S., Maglorius Renkilaraj, M. R. L., Ogishi, M., Soudée, C., COVID Human Genetic Effort (Ozcelik, T.), … Puel, A. (2023). Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. Nature, 623(7988), 803–813.

Sahin, A., Kara-Aksay, A., Bicmen, C., Belkaya, S., Kaya, A., & Yilmaz, D. (2023). Isolated Subcutaneous Abscess: A Rare Presentation of Extrapulmonary Tuberculosis. The Pediatric Infectious Disease Journal, 42(8), e316–e318.

Beyaz, Ş., Belkaya, S., & Öztop, N. (2023). Circulating Pentraxin-3 and its association with C-reactive protein levels and disease activity in patients with chronic spontaneous urticaria. Allergologia et Immunopathologia, 51(4), 87–93.

Üstündağ, G., Şahin, A., Yazıcı, Y. Y., Kara Aksay, A., Biçmen, C., Belkaya, S., & Yılmaz, D. (2023). Mycobacterium bovis’e Bağlı Zoonotik Pulmoner Tüberküloz Tanılı Bir İnfant [An Infant with Zoonotic Pulmonary Tuberculosis due to Mycobacterium bovis]. Mikrobiyoloji Bulteni, 57(3), 473–480.

Yazıcı, Y. Y., Belkaya, S., & Timucin, E. (2023). A small non-interface surface epitope in human IL18 mediates the dynamics and self-assembly of IL18-IL18BP heterodimers. Computational and Structural Biotechnology Journal, 21, 3522–3531.

García-García, A., Pérez de Diego, R., Flores, C., Rinchai, D., Solé-Violán, J., Deyà-Martínez, À., García-Solis, B., Lorenzo-Salazar, J. M., Hernández-Brito, E., Lanz, A. L., Moens, L., Bucciol, G., Almuqamam, M., Domachowske, J. B., Colino, E., Santos-Perez, J. L., Marco, F. M., Pignata, C., Bousfiha, A., Turvey, S. E., COVID Human Genetic Effort (Ozcelik, T.) … Rodríguez-Gallego, C. (2023). Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia. The Journal of Experimental Medicine, 220(5), e20220170.

Matuozzo, D., Talouarn, E., Marchal, A., Zhang, P., Manry, J., Seeleuthner, Y., Zhang, Y., Bolze, A., Chaldebas, M., Milisavljevic, B., Gervais, A., Bastard, P., Asano, T., Bizien, L., Barzaghi, F., Abolhassani, H., Abou Tayoun, A., Aiuti, A., Alavi Darazam, I., Allende, L. M., COVID Human Genetic Effort (Ozcelik, T.) … Cobat, A. (2023). Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. Genome Medicine, 15(1), 22.

Papadopoulos, N., Nédélec, A., Derenne, A., Şulea, T. A., Pecquet, C., Chachoua, I., Vertenoeil, G., Tilmant, T., Petrescu, A.-J., Mazzucchelli, G., Iorga, B. I., Vertommen, D., & Constantinescu, S. N. (2023). Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation. Nature Communications, 14(4), 1881.

Gök, V., Erdem, Ş., Haliloğlu, Y., Bişgin, A., Belkaya, S., Başaran, K. E., Canatan, M. F., Özcan, A., Yılmaz, E., Acıpayam, C., Karakükcü, M., Canatan, H., Per, H., Patıroğlu, T., Eken, A., & Ünal, E. (2023). Immunodeficiency associated with a novel functionally defective variant of SLC19A1 benefits from folinic acid treatment. Genes and Immunity, 24(1), 12–20

Korol, C. B., Belkaya, S., Alsohime, F., Lorenzo, L., Boisson-Dupuis, S., Brancale, J., Neehus, A. L., Vilarinho, S., Zobaida, A., Halwani, R., Al-Muhsen, S., Casanova, J. L., & Jouanguy, E. (2023). Fulminant Viral Hepatitis in Two Siblings with Inherited IL-10RB Deficiency. Journal of Clinical Immunology, 43(2), 406–420.

Lee, D., Le Pen, J., Yatim, A., Dong, B., Aquino, Y., Ogishi, M., Pescarmona, R., Talouarn, E., Rinchai, D., Zhang, P., Perret, M., Liu, Z., Jordan, I., Elmas Bozdemir, S., Bayhan, G. I., Beaufils, C., Bizien, L., Bisiaux, A., Lei, W., Hasan, M., Belkaya, S., COVID Human Genetic Effort (Ozcelik, T.) … Casanova, J. L. (2023). Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. Science (New York, N.Y.), 379(6632), eabo3627.

Pecquet, C., Papadopoulos, N., Balligand, T., Chachoua, I., Tisserand, A., Vertenoeil, G., Nédélec, A., Vertommen, D., Roy, A., Marty, C., Nivarthi, H., Defour, J. P., El-Khoury, M., Hug, E., Majoros, A., Xu, E., Zagrijtschuk, O., Fertig, T. E., Marta, D. S., Gisslinger, H., … Constantinescu, S. N. (2023). Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms. Blood, 141(8), 917–929.

Yazar, V., Yilmaz, I. C., Bulbul, A., Klinman, D. M., & Gursel, I. (2023). Gene network landscape of mouse splenocytes reveals integrin complex as the A151 ODN-responsive hub molecule in the immune transcriptome. Molecular Therapy Nucleic Acids, 31, 553–565.

Isik, O. A., & Cizmecioglu, O. (2023). Rafting on the Plasma Membrane: Lipid Rafts in Signaling and Disease. Advances in Experimental Medicine and Biology. Advance online publication.

Nakadai, T., Shimada, M., Ito, K., Cevher, M. A., Chu, C. S., Kumegawa, K., Maruyama, R., Malik, S., & Roeder, R. G. (2023). Two target gene activation pathways for orphan ERR nuclear receptors. Cell Research,  33(1), 165–183.

Tepe, Z. G., Yazıcı, Y. Y., Tank, U., Köse, L. I., Özer, M., Aytekin, C., & Belkaya, S. (2023). Inherited IRAK-4 Deficiency in Acute Human Herpesvirus-6 Encephalitis. Journal of Clinical Immunology, 43(1), 192–205.

Datta, R. R., & Onal, P. (2023). In Situ Hybridization as a Method to Examine Gene Regulatory Activity In Vivo. Methods in Molecular Biology (Clifton, N.J.), 2599, 241–254.

Zhang, Q., Pizzorno, A., Miorin, L., Bastard, P., Gervais, A., Le Voyer, T., Bizien, L., Manry, J., Rosain, J., Philippot, Q., Goavec, K., Padey, B., Cupic, A., Laurent, E., Saker, K., Vanker, M., Särekannu, K., COVID Human Genetic Effort (Ozcelik, T.), Etablissement Français du Sang Study Group, Constances Cohort, … Casanova, J. L. (2022). Autoantibodies against type I IFNs in patients with critical influenza pneumonia. The Journal of Experimental Medicine, 219(11).

Bolze, A., Mogensen, T. H., Zhang, S. Y., Abel, L., Andreakos, E., Arkin, L. M., Borghesi, A., Brodin, P., Hagin, D., Novelli, G., Okada, S., Peter, J., Renia, L., Severe, K., Tiberghien, P., Vinh, D. C., COVID human genetic effort (Ozcelik, T.), Cirulli, E. T., Casanova, J. L., & Hsieh, E. (2022). Decoding the Human Genetic and Immunological Basis of COVID-19 mRNA Vaccine-Induced Myocarditis. Journal of Clinical Immunology, 1–6.

Kabbani, M., Michailidis, E., Steensels, S., Fulmer, C. G., Luna, J. M., Le Pen, J., Tardelli, M., Razooky, B., Ricardo-Lax, I., Zou, C., Zeck, B., Stenzel, A. F., Quirk, C., Foquet, L., Ashbrook, A. W., Schneider, W. M., Belkaya, S., Lalazar, G., Liang, Y., Pittman, M., … de Jong, Y. P. (2022). Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice. Cell Reports, 40(11), 111321.

Korol, C. B., Belkaya, S., Alsohime, F., Lorenzo, L., Boisson-Dupuis, S., Brancale, J., Neehus, A. L., Vilarinho, S., Zobaida, A., Halwani, R., Al-Muhsen, S., Casanova, J. L., & Jouanguy, E. (2022). Fulminant Viral Hepatitis in Two Siblings with Inherited IL-10RB Deficiency. Journal of Clinical Immunology.

Özçelik, E., Kalaycı, A., Çelik, B., Avcı, A., Akyol, H., Kılıç, İ. B., Güzel, T., Çetin, M., Öztürk, M. T., Çalışkaner, Z. O., Tombaz, M., Yoleri, D., Konu, Ö., & Kandilci, A. (2022). Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2. PloS One, 17(10), e0275476.

Yildirim, A. D., Citir, M., Dogan, A. E., Veli, Z., Yildirim, Z., Tufanli, O., Traynor-Kaplan, A., Schultz, C., & Erbay, E. (2022). ER Stress-Induced Sphingosine-1-Phosphate Lyase Phosphorylation Potentiates the Mitochondrial Unfolded Protein Response. Journal of Lipid Research, 63(10), 100279.