Özhan Öçal



Faculty Member

Office: SB-248
Phone: +90 312 290 2056
E-mail: ozhan.ocal@bilkent.edu.tr
Google Scholar profile
ORCID profile
PubMed entries


Özhan Öçal obtained his BSc degree from Department of Molecular Biology and Genetics of Bilkent University in 2006. He went to Graduate School of University of Texas Medical Center in Dallas, TX, in USA and obtained his PhD degree in 2011 from its Genetics and Development program. During his graduate school and postdoctoral studies at University of Texas Medical Center, he worked on identification of early markers of diabetes mellitus and pancreatic cancer and outcome of chemotherapeutic drugs using mouse models. He came back to Department of Molecular Biology and Genetics of Bilkent University in 2018 as full time instructor.

Key Publications

Layeghi-Ghalehsoukhteh, S., Pal Choudhuri, S., Ocal, O., Zolghadri, Y., Pashkov, V., Niederstrasser, H., Posner, B. A., Kantheti, H. S., Azevedo-Pouly, A. C., Huang, H., Girard, L., MacDonald, R. J., Brekken, R. A., & Wilkie, T. M. (2020). Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics. Scientific Reports, 10(1), 20662.

Zolghadri, Y., Pal Choudhuri, S., Ocal, O., Layeghi-Ghalehsoukhteh, S., Berhe, F., Hale, M. A., & Wilkie, T. M. (2018). Malnutrition in Pancreatic Ductal Adenocarcinoma (PDA): Dietary Pancreatic Enzymes Improve Short-Term Health but Stimulate Tumor Growth. The American Journal of Pathology, 188(3), 616–626.

Wieczorek, M., Tcherkezian, J., Bernier, C., Prota, A. E., Chaaban, S., Rolland, Y., Godbout, C., Hancock, M. A., Arezzo, J. C., Ocal, O., Rocha, C., Olieric, N., Hall, A., Ding, H., Bramoullé, A., Annis, M. G., Zogopoulos, G., Harran, P. G., Wilkie, T. M., Brekken, R. A., … Roulston, A. (2016). The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Science Translational Medicine, 8(365).

Ocal, O., Pashkov, V., Kollipara, R. K., Zolghadri, Y., Cruz, V. H., Hale, M. A., Heath, B. R., Artyukhin, A. B., Christie, A. L., Tsoulfas, P., Lorens, J. B., Swift, G. H., Brekken, R. A., & Wilkie, T. M. (2015). A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics. Disease Models & Mechanisms, 8(10), 1201–1211.

Villasenor, A., Wang, Z. V., Rivera, L. B., Ocal, O., Asterholm, I. W., Scherer, P. E., Brekken, R. A., Cleaver, O., & Wilkie, T. M. (2010). Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes. Disease Models & Mechanisms, 3(9-10), 567–580.